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Key enzyme

Tyrosinase and pigmentation

Tyrosinase catalyses early steps in melanin production. Its activity is necessary for pigmentation but is only one element in a complex system.

In breve

Punti essenziali

  • Enzyme in melanogenesis
  • Acts on tyrosine
  • Requires cellular coordination
  • Does not explain autoimmunity
01

A precise biological role

Tyrosinase supports the conversion of pigment precursors inside melanosomes. Copper is one of the nutrients that contributes to normal pigmentation under an authorised EU claim.

02

Avoid overinterpreting ingredients

Knowing that a nutrient or cosmetic ingredient relates to this pathway does not demonstrate that it treats vitiligo or guarantees repigmentation.

Base editoriale

Editorial basis: current AWMF S2k guideline on the diagnosis and treatment of vitiligo, register 013-093, version 2.0 dated 27 July 2026. Reviewed on 2 September 2026.

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