In brief
Key points
- ✓Occurs in melanosomes
- ✓Tyrosinase is important
- ✓Pigment is transferred
- ✓Process is tightly regulated
From amino acid to pigment
Tyrosinase helps initiate reactions involving tyrosine. Additional enzymes and cellular conditions influence the type and quantity of melanin produced.
Transfer to the epidermis
Mature melanosomes move through melanocyte extensions into keratinocytes, where pigment contributes to colour and UV response.
Editorial basis: current AWMF S2k guideline on the diagnosis and treatment of vitiligo, register 013-093, version 2.0 dated 27 July 2026. Reviewed on 2 September 2026.
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