Clearly explainedEvidence-based guidance

Common question

Why do body areas repigment differently?

The face and neck often respond more readily than hands and feet, partly because hair follicles provide cellular reservoirs.

In brief

Key points

  • Face often responds better
  • Hands and feet are difficult
  • Follicles matter
  • No guaranteed response
01

The role of follicles

Repigmentation often begins as dots around hairs. Areas with few follicles, especially fingers and toes, have fewer potential reservoirs.

02

Other influences

Duration, activity, white hairs, type of vitiligo, consistency and treatment also affect results.

Editorial basis

Editorial basis: current AWMF S2k guideline on the diagnosis and treatment of vitiligo, register 013-093, version 2.0 dated 27 July 2026. Reviewed on 2 September 2026.

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